Damage Control Surgery after Burn Injury: A Narrative Review.

IF 1 Q4 CRITICAL CARE MEDICINE European burn journal Pub Date : 2022-04-01 DOI:10.3390/ebj3020024
Hans-Oliver Rennekampff, Mayer Tenenhaus
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Abstract

Burn injuries with cutaneous loss result in a severe systemic response when profound injuries exceed 20% of the total body surface area. The management of severely burned patients is a complex and dynamic process. Timely and safe operative interventions are critical components of multidisciplinary care. Effective management of severely burned patients, their cutaneous injuries, and the associated systemic disease requires a comprehensive understanding of the pathophysiologic response to trauma, objective indicators of patient status, and an appreciation for the dynamic nature of these parameters. Progress in both clinical and basic science research has advanced our understanding of these concepts and our approach to the management of burn patients. Incorporating concepts such as early total care, damage control surgery (DCS), and safe definitive surgery (SDS) in the polytraumatized patient may further aid in optimizing outcomes and quality of care for burn patients. This article connects current knowledge of the lethal triad, inflammation, immunosuppression, and eschar-derived toxins, with surgical burn care, especially burn wound debridement. The concepts of DCS and SDS for the care and management of burn patients are strongly advocated. Experimental and clinical studies are encouraged to validate these concepts in an effort to optimize patient outcomes.

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烧伤后的损伤控制手术:叙述性综述。
当烧伤面积超过体表总面积的 20% 时,皮肤缺损会导致严重的全身反应。严重烧伤患者的治疗是一个复杂而动态的过程。及时、安全的手术干预是多学科护理的关键组成部分。要有效治疗严重烧伤患者、其皮肤损伤以及相关的全身性疾病,需要全面了解创伤的病理生理反应、患者状态的客观指标以及这些参数的动态性质。临床和基础科学研究的进步推动了我们对这些概念和烧伤患者治疗方法的理解。将早期整体护理、损伤控制手术(DCS)和安全最终手术(SDS)等概念纳入多创面患者的治疗中,可进一步帮助优化烧伤患者的治疗效果和护理质量。这篇文章将当前关于致命三要素(炎症、免疫抑制和焦痂衍生毒素)的知识与烧伤外科护理,尤其是烧伤创面清创联系起来。文章大力提倡将 DCS 和 SDS 概念用于烧伤患者的护理和管理。我们鼓励通过实验和临床研究来验证这些概念,从而优化患者的治疗效果。
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Lost Work Due to Burn-Related Disability in a US Working Population. Development of Biofidelic Skin Simulants Based on Fresh Cadaveric Skin Tests. Bromelain in Burn Care: Advancements in Enzymatic Debridement and Patient Outcomes. 26 Years of Skin Banking in Finland. Life Satisfaction After Burn Injury-A Comprehensive Review.
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