Adherence to Anti-retroviral Therapy among HIV Positive Pregnant Women in Ayder Refferal Hospital, Northern Ethiopia

W. Shibabaw, Wondim Melkam, Agumas Shiabbaw
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引用次数: 9

Abstract

Background: Human Immunodeficiency Virus (HIV) is one of the major global public health problems. Antiretroviral therapy (ART) helps to prevent transmission of HIV from infected pregnant women to the un-born babies. ART adherence rate, as high as 95% is crucial to effectively decrease maternal viral load and risk of vertical transmission of HIV. The aim of this study was to evaluate ART adherence level among HIV positive pregnant women in Ayder referral hospital.Methods: A cross-sectional study was conducted from March to May 2016 at Ayder referral hospital. All HIV positive pregnant women who were on ART follow up during the study period were included. Data were collected through direct interview of participants and review of their medical records. Data were entered and analyzed using SPSS version 20 software.Results: A total of 41 HIV-positive pregnant women were interviewed. The mean age was 30.1 ± 2.3 years. Thirty eight (92.7%) participants were within the age group of 20-34 years. Forty participants (97.6%) were disclosed their HIV status to their husband and/or families. Nineteen (46.3%) participants were taking ART medication for less than 2 years. Thirty nine participants had good adherence rate (≥ 95%). Illiterate participants had lower adherence rate (71.4%) as compared to literates. The common reasons for missing a dose in the last one month were forgetfulness and side effect of the drug.Conclusions: This study showed a good ART adherence among HIV positive pregnant women. The main reasons for missing a dose in the last one month were forgetfulness and side effect of the drug.
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埃塞俄比亚北部艾德尔转诊医院艾滋病毒阳性孕妇坚持抗逆转录病毒治疗的情况
背景:人类免疫缺陷病毒(HIV)是全球主要的公共卫生问题之一。抗逆转录病毒疗法(ART)有助于防止受感染孕妇将艾滋病毒传染给未出生的婴儿。高达95%的抗逆转录病毒治疗依从率对于有效降低孕产妇病毒载量和艾滋病毒垂直传播风险至关重要。本研究的目的是评估艾德尔转诊医院HIV阳性孕妇的抗逆转录病毒治疗依从性。方法:2016年3月至5月在艾德尔转诊医院进行横断面研究。所有在研究期间接受抗逆转录病毒治疗随访的艾滋病毒阳性孕妇都被纳入研究范围。数据是通过直接采访参与者和审查他们的医疗记录收集的。使用SPSS 20版软件进行数据录入和分析。结果:共访谈41例hiv阳性孕妇。平均年龄30.1±2.3岁。38名(92.7%)参与者年龄在20-34岁之间。40名参与者(97.6%)向其丈夫和/或家人披露了其艾滋病毒状况。19名(46.3%)参与者服用抗逆转录病毒药物少于2年。39名参与者有良好的依从率(≥95%)。文盲参与者的依从率(71.4%)较文盲参与者低。最近一个月未服药的常见原因是健忘和药物副作用。结论:本研究显示HIV阳性孕妇抗逆转录病毒治疗依从性良好。最近一个月未服药的主要原因是健忘和药物副作用。
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