Melanoma: what the primary care physician needs to know

Eric Jonasch MD
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Abstract

Melanoma is a serious public health issue. More than 53,000 individuals will be diagnosed with this potentially devastating disease in 2002, making it one of the fastest-growing cancer risks in the country. Diagnosis and management at an early stage result in an excellent outcome in most patients, but more advanced stages of this disease can portend a dire prognosis. In this review, melanoma pathology, risk factors, staging, and treatment are reviewed. Screening, prevention, and early detection are discussed. Diagnosis and management of melanoma before, during, and after pregnancy is a controversial topic that is covered in this review, as is the safety of hormone replacement therapy in patients with melanoma. A combination of preventive behavior, vigilance, and appropriate management before, during, and after pregnancy can result in decreased risk and improved outcomes.

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黑色素瘤:初级保健医生需要知道的
黑色素瘤是一个严重的公共卫生问题。2002年,将有超过53,000人被诊断患有这种潜在的毁灭性疾病,使其成为该国增长最快的癌症风险之一。早期诊断和治疗在大多数患者中都有很好的结果,但更晚期的疾病可能预示着可怕的预后。在这篇综述中,黑色素瘤的病理,危险因素,分期和治疗进行了回顾。讨论了筛查、预防和早期发现。黑素瘤的诊断和治疗在怀孕前、怀孕期间和怀孕后都是一个有争议的话题,黑素瘤患者激素替代治疗的安全性也是一个有争议的话题。在怀孕前、怀孕期间和怀孕后,预防行为、警惕和适当管理相结合,可以降低风险并改善结果。
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