Enhancement of Anti-inflammatory Activities of Aronia melanocarpa through High-pressure Homogenization Process

H. Lee
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Abstract

It was first confirmed that the increase of anti-inflammatory activities of Aronia melanocarpa from high-pressure homogenization at 25,000 psi and 25°C was caused by the three times higher extraction of very heat-labile cyanidin-3-O-galactoside (C3G), a bioactive anthocyanin existing in A. melanocarpa, than that of conventional 70% ethanol extraction at 80°C. The extracts from this process showed better efficacies in suppressing the production of both nitric oxide and the cytokines, IL-6 and TNF-α, and resulted in high liver weight gain in mice. This result could be employed to extract other heat-sensitive components from various bioresources.
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高压均质工艺增强黑檀抗炎活性
首先证实,在25000 psi和25°C高压均质条件下,黑果野莓抗炎活性的增强是由于在80°C条件下提取的非常热不稳定的花青素-3- o -半乳糖苷(C3G)比传统的70%乙醇提取高3倍。该工艺的提取物对一氧化氮和细胞因子IL-6、TNF-α的产生均有较好的抑制作用,并导致小鼠肝脏增重。该结果可用于从各种生物资源中提取其他热敏成分。
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来源期刊
Journal of Residuals Science & Technology
Journal of Residuals Science & Technology 环境科学-工程:环境
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>36 weeks
期刊介绍: The international Journal of Residuals Science & Technology (JRST) is a blind-refereed quarterly devoted to conscientious analysis and commentary regarding significant environmental sciences-oriented research and technical management of residuals in the environment. The journal provides a forum for scientific investigations addressing contamination within environmental media of air, water, soil, and biota and also offers studies exploring source, fate, transport, and ecological effects of environmental contamination.
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