Whole genome sequencing of disease animal models

Abstract

Whole genome sequencing of disease animal models together with population genetics methodology is a powerful technology for deciphering new variations which associated with disease phenotypes. Here we show our studies on camel, dog, and rabbit. Whole genome sequencing data were generated from those animals, and then population genetics methodology was used in dealing with these whole genome sequencing date. Some important genetic variations were discovered which shown a strong association with disease related phenotypes.