Comparison of 3DCRT Dose Distribution in Radiotherapy for Lung Cancer Patient by Using AAA and PBC Algorithms

M. M. Rana, S. Islam, Monirul Islam, Md. Shakilur Rahman, S. Alam, M. Bari
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Abstract

The Pencil Beam Convolution (PBC) algorithm in radiation treatment planning system is widely used to calculate the radiation dose distribution in radiotherapy planning. A new photon dose calculation algorithm known as Anisotropic Analytical Algorithm (AAA) by Varian Medical Systems is applied to investigate the difference of dose distribution by using AAA and PBC algorithms for the lung cancer with an inhomogeneity of its low density. In the present work, radiotherapy treatment planning of 10 lung cancer patients are designed with 6 MV photon beam using three-dimensional conformal radiation therapy (3DCRT) and dose distribution was calculated by the AAA and the PBC Algorithms. The dose distribution performance is evaluated by dose profile curve along transversal slice of PTV and Dose Volume Histogram (DVH) covered by the 95% isodose of PTV. The mean dose of organ at risks did not changed significantly but the volume of the PTV covered by the 95% isodose curve was decreased by 6% with inhomogeneity due to the algorithms. The dose distribution and the accuracy in calculating the absorbed dose of the AAA algorithm of the Varian Eclipse treatment planning system is analyzed and discussed.
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应用AAA与PBC算法对肺癌患者放疗3DCRT剂量分布的比较
放射治疗计划系统中的铅笔束卷积(Pencil Beam Convolution, PBC)算法被广泛用于放射治疗计划中辐射剂量分布的计算。应用Varian Medical Systems提出的一种新的光子剂量计算算法——各向异性分析算法(AAA),研究低密度非均匀肺癌的剂量分布差异。本文采用三维适形放射治疗(3DCRT),设计了10例肺癌患者的6 MV光子束放射治疗方案,并采用AAA和PBC算法计算剂量分布。通过PTV横向切片的剂量曲线和PTV 95%等剂量覆盖的剂量体积直方图(DVH)来评价剂量分布性能。危险器官的平均剂量没有显著变化,但95%等剂量曲线覆盖的PTV体积减少了6%,由于算法的不均匀性。对瓦里安日蚀治疗计划系统的AAA算法的剂量分布及计算吸收剂量的准确性进行了分析和讨论。
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