Use of Redness Assessment in Melasma Lesions in Skin Whitening Evaluation

J. Lee, J. Y. Kim, Sun Hwa Lee, Bo-ra Kim, Nam Soo Kim, T. K. Moon
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Abstract

: Melasma has several well-recognized etiologic factors, but most researches focus on melanogenesis. The purpose of this study is to show improvement of melasma by reducing vascularity distinguished from melanogenesis. We examined 20 Korean women with both melasma and solar lentigo that were visually assessed by a dermatologist. The volunteers applied functional cosmetics for 8 weeks. We analyzed the results obtained using the chromameter, evaluating the skin color of three areas (melasma lesions, solar lentigo lesions, and non-lesional skin) on the face of volunteer. There was a statistically significant improvement in the brightness and redness of melasma lesions compared to those of non-lesional skin after 8 weeks. Also, we observed that the improvements in the brightness of melasma lesions and solar lentigo lesions were similar. However, the redness of melasma lesions improved more than that of solar lentigo lesions with statistical significance after 8 weeks. In this study, we have shown that brightness and redness in melasma lesions can be improved by functional cosmetics. Thus, we suggest redness to be an additional suitable parameter for the evaluation of melasma lesions.
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黄褐斑病变发红评价在皮肤美白评价中的应用
黄褐斑有几个公认的病因,但大多数研究集中在黑色素形成上。本研究的目的是通过减少与黑色素形成不同的血管来改善黄褐斑。我们检查了20名同时患有黄褐斑和太阳色斑的韩国女性,并由皮肤科医生进行了视觉评估。志愿者使用功能性化妆品8周。我们分析了使用色度计获得的结果,评估了志愿者脸上三个区域(黄褐斑病变,太阳色斑病变和非病变皮肤)的皮肤颜色。8周后,与非病变皮肤相比,黄褐斑病变的亮度和红度有统计学意义的改善。此外,我们观察到黄褐斑病变和太阳色斑病变亮度的改善是相似的。但8周后黄褐斑病变红肿程度改善明显,差异有统计学意义。在本研究中,我们发现功能性化妆品可以改善黄褐斑病变的亮度和红色。因此,我们建议将红肿度作为评估黄褐斑病变的另一个合适参数。
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