An audit of pain scores with conventional and white light topical 5‐methyl aminolaevulinic acid photodynamic therapy for superficial basal cell carcinoma and squamous cell carcinoma in situ
R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins
{"title":"An audit of pain scores with conventional and white light topical 5‐methyl aminolaevulinic acid photodynamic therapy for superficial basal cell carcinoma and squamous cell carcinoma in situ","authors":"R. Hellen, E. Nic Dhonncha, A. Havelin, L. Fleming, A. Kavanagh, A. Lally, B. Kirby, B. Moriarty, P. Collins","doi":"10.1111/phpp.12521","DOIUrl":null,"url":null,"abstract":"Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"92 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/phpp.12521","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Conventional PDT (c-PDT) is an effective treatment for diffuse actinic keratoses, superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). The prodrug (5-methyl aminolaevulinic acid, MAL) is applied to the treatment area for three hours before exposure to 50 J/cm2 red light (615-645 nm) at 50 mW/cm2 from light emitting diode (LED) lamps (Aktilite CL128 and Omnilux PDT). Patients receive two treatments one week apart. The main drawback is pain. Various approaches have been investigated to reduce pain scores in PDT, including alternative light sources and protocols.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
