J. Njoku, T. V. Van Schooneveld, M. Rupp, K. Olsen, F. Qiu, J. Meza, E. Hermsen
{"title":"Lack of Benefit With Combination Therapy for Clostridium difficile Infection","authors":"J. Njoku, T. V. Van Schooneveld, M. Rupp, K. Olsen, F. Qiu, J. Meza, E. Hermsen","doi":"10.1017/ice.2016.320","DOIUrl":null,"url":null,"abstract":"Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03–1.44 days; P=.02). Infect Control Hosp Epidemiol 2017;38:602–605","PeriodicalId":13655,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"28 1","pages":"602 - 605"},"PeriodicalIF":0.0000,"publicationDate":"2017-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infection Control & Hospital Epidemiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1017/ice.2016.320","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03–1.44 days; P=.02). Infect Control Hosp Epidemiol 2017;38:602–605