The Study of Semen Quality for Evaluation of Male Factor Infertility

Mafruha Khanam, Aditi Banerjee, J. Jerin, Mohamed Mazih Fazyl
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Abstract

Background: The global infertility rates are increasing at an alarming pace.Standard semen analysis is the basic and initial investigation in clinical practice for understanding male infertility. The objective of this study is to evaluate male infertility by studying the quality of semen according to the WHO protocols, identify the semen abnormalities to correlate the relationship between semen parameters and infertile couples. Materials and methods: This is a cross-sectional prospective study conducted in Surgiscope Fertility Centre, Chattogram, Bangladesh over 9 months on 1348 couples who received services from the fertility centre from November 2018 to July 2019. Multiple variables were selected such as, patient parameters like age of the couple, smoking history, duration of infertility, semen abnormalities which were recorded and statistically analyzed. The procedure and reference values were according to the WHO guidelines 2010. Results: The minimum age of the patients was 19 and the maximum age of the patients was 60 with a mean age of 33.3 +/- 0.5 years.The majority of the patients whose wives conceived were between the ages of 34 to 44 years and the lowest number of patients whose wives conceived were 55+ years. Moreover,359 patients (26.63%) conceived while 989 patients (73.37%) did not conceive.No significant relationship between number of conceptions and addiction was recorded. There is a statistically significant negative relationship between total motile sperm and age of patient and a marginally positive relationship between the number of sperm and total motility.    Conclusion: This study showed a higher incidence of abnormal semen quality among husbands of infertile couples in our population. This revealed the importance of emphasizing on the need for managing male infertility. JCMCTA 2020 ; 31 (1) : 13-18
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精液质量评价男性因素性不育症的研究
背景:全球不孕率正以惊人的速度增长。标准精液分析是临床认识男性不育症的基础和初步研究。本研究的目的是通过研究精液质量来评估男性不育症,确定精液异常,并将精液参数与不育夫妇之间的关系联系起来。材料和方法:这是一项横断面前瞻性研究,于2018年11月至2019年7月在孟加拉国Chattogram的外科生育中心对1348对夫妇进行了为期9个月的研究,这些夫妇从生育中心接受了服务。选取夫妇年龄、吸烟史、不孕持续时间、精液异常等患者参数进行记录和统计分析。程序和参考值根据2010年世卫组织指南。结果:患者最小年龄19岁,最大年龄60岁,平均年龄33.3±0.5岁。妻子怀孕的患者以34 ~ 44岁居多,年龄55岁以上的患者最少。妊娠359例(26.63%),未妊娠989例(73.37%)。概念数量与成瘾之间无显著关系。精子总活动数与患者年龄呈显著负相关,精子总活动数与患者年龄呈微弱正相关。结论:本研究显示我国不育夫妇的丈夫精液质量异常发生率较高。这显示了强调管理男性不育症的必要性的重要性。Jcmcta 2020;31 (1): 13-18
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