{"title":"Impaired Phenotype of Circulating Endothelial-Derived Microparticles: Novel Marker of Cardiovascular Risk","authors":"A. Berezin","doi":"10.17554/J.ISSN.2309-6861.2015.02.78","DOIUrl":null,"url":null,"abstract":"Circulating microparticles (MPs) delivered from the native cell membrane are suitable forms of cell-to-cell communication and transfer of biological active effectors. Circulating endothelial-derived MPs as a marker of endothelial dysfunction may discuss as integrated effectors interrelated target cells, endothelium, and conventional cardiovascualr risk factors. Endothelial-derived MPs play a pivotal role in vascular damage, integrity and tissue reparation. However, the role of MPs as biomarker of cardiovascular outcomes is required scrutinizes. The present review accumulates data regarding the role of circulating endothelial-derived MPs as novel marker of cardiovascular risk.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"4565 3 1","pages":"365-370"},"PeriodicalIF":0.0000,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"35","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical cardiology and cardiovascular therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17554/J.ISSN.2309-6861.2015.02.78","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 35
Abstract
Circulating microparticles (MPs) delivered from the native cell membrane are suitable forms of cell-to-cell communication and transfer of biological active effectors. Circulating endothelial-derived MPs as a marker of endothelial dysfunction may discuss as integrated effectors interrelated target cells, endothelium, and conventional cardiovascualr risk factors. Endothelial-derived MPs play a pivotal role in vascular damage, integrity and tissue reparation. However, the role of MPs as biomarker of cardiovascular outcomes is required scrutinizes. The present review accumulates data regarding the role of circulating endothelial-derived MPs as novel marker of cardiovascular risk.
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