Inhaled Sevofluran vs Endovenous Propofol for Sedation Maintenance in Patients Submitted to Colonoscopy

Abstract

Introduction: Endoscopic procedures under sedation currently occupy an important place. Sedation allows optimal conditions for the study Objective: To compare the anesthetic efficacy of the inhalation versus intravenous technique for maintenance of sedation in patients undergoing endoscopy. Materials and methods: A longitudinal, randomized clinical study of 32 patients of both sexes ASA I-III, aged 18-80 years undergoing diagnostic colonoscopy, which was randomly divided into 2 groups. In both, intravenous induction with propofol (2-2.5 mg / kg) was performed, Group A remained sedated with propofol infusion (1-2 mg / kg / min); Group B by inhalation with sevoflurane at a concentration of 2 vol% through a nasal cannula with an oxygen flow. Results: Both techniques were performed without registering complications; group A comprised of 15 patients in which only 13% required rescue bolus and a wake-up time of 12 minutes. The group B consisted of 17 patients, with a wake-up time of 7 minutes in whom 35% required salvage bolus. Conclusion: Both anesthetic techniques proved to be safe and effective; patients receiving sevoflurane shortened their stay by 50% in the recovery of the endoscopic unit. Patients who only received propofol presented greater anesthetic depth required a lower rate of rescue boluses. Both techniques evidenced a good comfort level in both the patients and gastroenterologists.