The Impact of 950mhz Electromagnetic Radiation on the Brain and Liver of Rats and the role of Garlic Treatment

S. Shedid, Ghada A. El-Tawill, Fatma R. Algeda, Neama N. El-Fatih, N. Eltahawy
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引用次数: 2

Abstract

The use of mobile phones, laptops and wireless networks has become essential components of daily life. However, despite they make life easier, they may also cause a number of health problems.This study aims at investigating the changes induced in the liver and brain of male albino rats caused by the exposure to 950MHz and the role of garlic treatment. Male Albino rats were exposed to 950MHz electromagnetic field (power density of 1mW/cm2). Whole body average specific absorption rates (SAR) were 0.238 and 0.372, respectively, for duration of one hour, thrice a week for a period of seven weeks. Garlic extract was administered to the rats at a doseof 500mg/kg body weight, half an hour before each exposure. Animals were sacrificed one day post the last exposure dose. Exposure to 950MHz has triggered oxidative stress in both tissues verified by a significant increase of malondialdehyde (MDA) and nitric oxide (NO) associated with a significant decrease in the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px). Exposure to 950MHz has also induced alteration in the xanthine oxidoreductase system (XOR) identified by a significant increase in the activity of xanthine oxidase (XO) concomitant to a significant decrease of xanthine dehydrogenase. The results showed also accumulation of iron (Fe), and cupper (Cu), and decreases in zinc (Zn) and manganese (Mn). Garlic extract treatment has significantly improved these changes. In conclusion, Garlic might attenuate the impact of 950MHz in liver and brain of male rats.
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950mhz电磁辐射对大鼠脑、肝的影响及大蒜的治疗作用
手机、笔记本电脑和无线网络的使用已经成为日常生活中必不可少的组成部分。然而,尽管它们使生活更容易,它们也可能导致一些健康问题。本研究旨在探讨950MHz暴露对雄性白化大鼠肝脏和大脑的影响及大蒜的作用。雄性白化病大鼠暴露于950MHz(功率密度1mW/cm2)的电磁场中。每隔1小时,每周3次,连续7周,全身平均比吸收率(SAR)分别为0.238和0.372。每次暴露前半小时,以500mg/kg体重的剂量给予大鼠大蒜提取物。动物在最后一次接触剂量后一天被处死。暴露于950MHz会引发两种组织的氧化应激,其结果是丙二醛(MDA)和一氧化氮(NO)显著增加,同时超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)活性显著降低。暴露于950MHz也诱导黄嘌呤氧化还原酶系统(XOR)的改变,黄嘌呤氧化酶(XO)活性显著增加,同时黄嘌呤脱氢酶显著降低。结果还显示铁(Fe)和铜(Cu)的积累,锌(Zn)和锰(Mn)的减少。大蒜提取物处理显著改善了这些变化。综上所述,大蒜可减轻950MHz对雄性大鼠肝脏和大脑的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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