{"title":"In Vitro Study of Experimental Ag-In Alloys with Embryo Stem Cell Test Protocol and Whole Embryo Culture","authors":"K. Imai, H. Takashima","doi":"10.11223/JARDE.12.127","DOIUrl":null,"url":null,"abstract":"127 INTRODUCTION Using the Embryo Stem Cell Test (EST) protocol , a embryotoxicity test with mouse ES-D3 cells, embryotoxicity was noted for several indium compounds . The EST protocol has already been validated in Europe, demonstrating a strong correlation with human teratogenicity . Although various indiumcontaining alloys have already been used for dental alloys , no report has been published on their embryotoxicity risk. Using Ag-20% In and Ag-Pd-Au-Cu In Vitro Study of Experimental Ag-In Alloys with Embryo Stem Cell Test Protocol and Whole Embryo Culture","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral tissue engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11223/JARDE.12.127","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
127 INTRODUCTION Using the Embryo Stem Cell Test (EST) protocol , a embryotoxicity test with mouse ES-D3 cells, embryotoxicity was noted for several indium compounds . The EST protocol has already been validated in Europe, demonstrating a strong correlation with human teratogenicity . Although various indiumcontaining alloys have already been used for dental alloys , no report has been published on their embryotoxicity risk. Using Ag-20% In and Ag-Pd-Au-Cu In Vitro Study of Experimental Ag-In Alloys with Embryo Stem Cell Test Protocol and Whole Embryo Culture