A Clinico Histopathological Study of Childhood Leprosy

D. Rao, Dr.G. Leelavathi, Dr. G. Purnima
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引用次数: 1

Abstract

Background: Leprosy is one of the oldest diseases known to mankind and is still associated with stigma. A high child proportion signifies active and recent transmission of the disease. Aim: To know the proportion of children in newly detected leprosy patients and their clinico histopathological categorisation. Methodology: This was a retrospective analysis of all leprosy patients less than 16 years of age registered at the Leprosy Clinic of GGH, Vijayawada from January2015-June2016. Results: Proportion of children among newly diagnosed leprosy patients was 9.2% .Majority of patients belonged to age group of 13 to 16 years(48%), with male preponderance. 24% patients gave family history of leprosy. 40% of patients belonged to PB type, 60% MB type. Slit skin smear was positive in 20%. According to clinical characteristics, majority of patients belonged to BT(52%) followed by TT(32%). According to histopathological characteristics majority of patients belonged to BT(48%) followed by TT(36%).Clinico Histopathological correlation in LL Hansen’s is 100%, in BT 76%.Type I reaction occurred in 2 patients(8%).Deformities were observed in 8% patients. Conclusion: Despite statistical elimination of leprosy, childhood leprosy still remains a public health problem. Early detection, treatment and contact tracing are important for reducing the burden of leprosy in the community.
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儿童麻风的临床组织病理学研究
背景:麻风病是人类已知的最古老的疾病之一,仍然与耻辱有关。儿童比例高表明该疾病的活跃和最近的传播。目的:了解儿童在新发麻风患者中的比例及其临床病理分型。方法:回顾性分析2015年1月至2016年6月在维杰亚瓦达GGH麻风诊所登记的所有16岁以下麻风患者。结果:新诊断麻风患者中儿童所占比例为9.2%,以13 ~ 16岁年龄组(48%)居多,男性居多。24%的患者有麻风病家族史。PB型占40%,MB型占60%。切口皮肤涂片阳性占20%。从临床特征来看,大部分患者属于BT(52%),其次是TT(32%)。根据组织病理学特征,大多数患者属于BT(48%),其次是TT(36%)。临床组织病理学相关性为100%,BT为76%。2例(8%)发生I型反应。8%的患者出现畸形。结论:尽管统计上已经消除了麻风病,但儿童麻风病仍然是一个公共卫生问题。早期发现、治疗和接触者追踪对于减轻社区麻风病负担非常重要。
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