N. Goelen, J. D. de Hoon, John F. Morales, C. Varon, S. Van Huffel, P. Augustijns, R. Mols, Marissa Herbots, K. Verbeke, T. Vanuytsel, J. Tack, P. Janssen
{"title":"Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter","authors":"N. Goelen, J. D. de Hoon, John F. Morales, C. Varon, S. Van Huffel, P. Augustijns, R. Mols, Marissa Herbots, K. Verbeke, T. Vanuytsel, J. Tack, P. Janssen","doi":"10.1111/nmo.13733","DOIUrl":null,"url":null,"abstract":"The use of opioids as analgesic is on the rise, despite their inhibitory effect on gastric emptying. A novel feeding catheter with integrated intragastric balloon was developed to continuously assess gastric motility, enabling to investigate the effect of opioids on motility and emptying simultaneously. We aimed to discriminate normal and pharmacologically impaired gastric motility and its impact on gastric emptying in healthy adults.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurogastroenterology & Motility","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/nmo.13733","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 14
Abstract
The use of opioids as analgesic is on the rise, despite their inhibitory effect on gastric emptying. A novel feeding catheter with integrated intragastric balloon was developed to continuously assess gastric motility, enabling to investigate the effect of opioids on motility and emptying simultaneously. We aimed to discriminate normal and pharmacologically impaired gastric motility and its impact on gastric emptying in healthy adults.
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