Prevalence of Molecular Breast Cancer Subtypes in Ethiopia: A Review

Bizualem Shenkutie, S. Solomon, Asmamawu Menilh
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Abstract

Breast cancer is a heterogeneous diseases and it is difficult to provide the right treatment. Molecular markers are good indicators for prognosis and predictive factor. Therefore, the current review was designed to assess the prevalence of Molecular subtypes of Breast cancer in Ethiopia. The review concentrated on current literature on Prevalence, Breast Cancer, Women, Molecular Subtypes, Hormone Receptors and Ethiopia with scientifically proven efficacy was carried out using electronic databases such as Science Direct, Google Scholar and PubMed. Among a total of 4000 studies, six studies were included in this review. The current review showed that the prevalence of ER+, PR+ and Luminal A Breast cancer is high in Ethiopia. For this reason Ethiopian breast cancer patients will be take hormonal therapy. However, further study should be done on the prevalence of molecular subtypes of breast cancer via PCR and other laboratory method for clearly identification of the molecular markers.
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分子乳腺癌亚型在埃塞俄比亚的流行:综述
乳腺癌是一种异质性疾病,很难提供正确的治疗。分子标记是良好的预后指标和预测因素。因此,本综述旨在评估埃塞俄比亚乳腺癌分子亚型的患病率。该综述利用Science Direct、谷歌Scholar和PubMed等电子数据库,集中分析了目前关于患病率、乳腺癌、妇女、分子亚型、激素受体和埃塞俄比亚的文献,这些文献具有科学证明的疗效。在4000项研究中,本综述纳入了6项研究。目前的综述显示,在埃塞俄比亚,ER+、PR+和Luminal A乳腺癌的患病率很高。因此,埃塞俄比亚的乳腺癌患者将接受激素治疗。但是,为了明确分子标记,还需要通过PCR等实验室方法对乳腺癌分子亚型的流行情况进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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