Gold Nanoparticles Embedded Microrobots for Real-time X-ray Imaging

B. Darmawan, Sang Bong Lee, Gwangjun Go, Chang-sei Kim, Doyeon Bang, Jong-Oh Park, Eunpyo Choi
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Abstract

Microrobots have been demonstrated to have the potential in medical approaches, such as for targeted drug delivery. However, real-time tracking and imaging are still one of the major issues faced by microrobots. Here, we fabricated helical microrobots based on self-folding technique, and we performed double coating of gold nanoparticles (AuNPs) to the surface of microrobots to enhance the image quality under X-ray. The result shows that, we successfully coated the AuNPs into the self-rolled microrobots, and it increases the image quality when compared to non-coated microrobots. Despite the fact that there still remain some challenges to achieve successful applications of microrobots, we believe that the potential of this study can contribute to reduce the challenges faces in the medical microrobot fields.
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用于实时x射线成像的金纳米颗粒嵌入微型机器人
微型机器人已被证明在医疗方法中具有潜力,例如靶向药物输送。然而,实时跟踪和成像仍然是微型机器人面临的主要问题之一。本文基于自折叠技术制备了螺旋微型机器人,并在微型机器人表面涂覆了金纳米粒子(AuNPs),以提高其x射线下的图像质量。结果表明,我们成功地将AuNPs涂覆到自滚微机器人中,与未涂覆的微机器人相比,它提高了图像质量。尽管实现微型机器人的成功应用仍然存在一些挑战,但我们相信本研究的潜力可以有助于减少医疗微型机器人领域面临的挑战。
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