Efficacy of darolac probiotic and chlorhexidine mouth rinse in reducing plaque and gingival inflammation in children: A clinical trial

Yogesh M. Bande, Sharda Ade, Sudhir Baroopal, Akshada Joshi, Janhabi Pathak, Abhinay I. Deshmukh, S. Arya
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引用次数: 2

Abstract

Background: Chemical agents have been increasingly used as an adjunct to mechanical control. The use of a mouthwash augments maintenance of oral health through its antiplaque and antibacterial chemical properties.Recently, Probiotics can be used an effective alternative for other traditional mouthrinses in reducing plaque accumulation and gingival inflammation. Aim: To evaluate the clinical efficacy of a probiotic and chlorhexidine mouth rinses on plaque and gingival accumulation in children. Materials and Methods: Randomized controlled 14 day trial including 30 healthy children (6–8 years) was done in which 10 children were in control group and 20 children were instructed to rinse 5ml/day for 1 min of each solution (probiotics and chlorhexidine) for 14 days. Results: A Statistically significanct difference was noted between mean PI and mean GI score of control group when compared with probiotic and chlorhexidine after 14 days in comparison to baseline (P < 0.001). However, there was no significant difference in mean plaque accumulation and gingival inflammation between the probiotics and chlorhexidine on the 14th day examination. Conclusion: Probiotics mouth rinse was effective in reducing plaque accumulation and gingival inflammation in 6 to 8 year old children.
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darolac益生菌和氯己定漱口水减少儿童菌斑和牙龈炎症的疗效:一项临床试验
背景:化学制剂越来越多地被用作机械控制的辅助手段。漱口水的使用通过其抗菌斑和抗菌的化学特性增强了口腔健康的维护。近年来,益生菌在减少牙菌斑积累和牙龈炎症方面,已成为其他传统漱口水的有效替代品。目的:评价一种益生菌联合氯己定漱口水对儿童牙菌斑和牙龈堆积的临床疗效。材料与方法:选取健康儿童30例(6-8岁)进行14天的随机对照试验,其中对照组10例,指导20例儿童分别用益生菌和氯己定溶液5ml/天冲洗1 min,连续14天。结果:对照组使用益生菌和氯己定治疗14天后PI和GI评分与基线比较差异有统计学意义(P < 0.001)。然而,在第14天的检查中,益生菌和氯己定在平均菌斑积累和牙龈炎症方面没有显著差异。结论:益生菌漱口水能有效减少6 ~ 8岁儿童牙菌斑堆积和牙龈炎症。
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