Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex

Q4 Biochemistry, Genetics and Molecular Biology Journal of Biomolecular Techniques Pub Date : 2023-06-27 DOI:10.51173/jt.v5i2.885
Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy
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Abstract

Chronic kidney disease is a worldwide health problem that is defined as structural abnormalities or progressive or permanent loss of renal function for 3 months or more, which is usually associated with a decrease in glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m2 or persistent proteinuria, which can lead to end-stage renal disease (ESRD) or kidney failure. To assess the risk factors leading to chronic kidney disease among the patients between cases and controls in the Medical City Complex. The study was conducted in hospitals of the medical city complex (Baghdad Teaching Hospital, Nursing Home Private Hospital, Ghazy Al-Hariri Hospital for Surgical Specialist, and kidney diseases and Transplant Center) in Baghdad, Iraq, and was designed as a case-control. There were 300 participants (150 cases and 150 controls). Data was collected over five months. The findings show that the highest percentage (20%) was within the age group 50–59 years old in the case study group, with a mean age of patients and controls of 47.71 ± 17.42 and 48.54 ± 17.43 years, respectively, and there were significant sociodemographic risk factors for CKD with gender and residency (p. value < 0.05). There was a significant link between medical history and the outcome of this investigation (p. value < 0.05 and OR > 1) All of the risk factors for CKD were hypertension, acute kidney disease, HCV infection, hyperlipidemia, renal stones, anemia, and cardiovascular disease. alcohol consumption had a significant difference with CKD (p. value =0.004). Increased intake of antihypertensive medical drugs also increases the risk of CKD (p. value =0.000). There is a significant association between patients' gender and residence, the patients with hypertension, AKI, HCV infection, hyperlipidemia, renal stones, anemia, and CVD had a significant relationship with CKD. The risk of CKD is increased in people who have had alcoholism and also in patients who have taken antihypertensive medication, The study recommends educating people about the risk factors of CKD, encouraging them to adopt a healthy diet, and healthy lifestyle, and encouraging alcohol cessation through special programs. The GFR test and other routine clinical tests must be performed regularly to monitor the change in kidney functions.
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医疗城综合医院慢性肾脏疾病危险因素评估
慢性肾病是一种全球性的健康问题,其定义为结构异常或进行性或永久性肾功能丧失3个月或更长时间,通常伴有肾小球滤过率(GFR)低于60 mL/min/1.73 m2或持续性蛋白尿,可导致终末期肾病(ESRD)或肾衰竭。目的探讨医疗城综合医院病例与对照患者慢性肾脏疾病的危险因素。该研究在伊拉克巴格达的医疗城综合医院(巴格达教学医院、私人疗养院医院、Ghazy Al-Hariri外科专科医院和肾脏疾病和移植中心)进行,并设计为病例对照。共有300名参与者(150例和150例对照)。数据是在五个月内收集的。结果显示,病例研究组中50-59岁年龄组患病率最高(20%),患者和对照组的平均年龄分别为47.71±17.42岁和48.54±17.43岁,性别和居住地存在显著的CKD社会人口学危险因素(p值< 0.05)。病史与调查结果之间存在显著联系(p值< 0.05,OR值> 1)。CKD的所有危险因素为高血压、急性肾病、HCV感染、高脂血症、肾结石、贫血和心血管疾病。饮酒与CKD有显著差异(p值=0.004)。抗高血压药物的摄入量增加也会增加CKD的风险(p值=0.000)。患者性别与居住地有显著相关性,高血压、AKI、HCV感染、高脂血症、肾结石、贫血、CVD患者与CKD有显著相关性。酗酒和服用降压药的患者患慢性肾病的风险增加。该研究建议教育人们了解慢性肾病的危险因素,鼓励他们采用健康的饮食和生活方式,并通过特殊计划鼓励戒酒。必须定期进行GFR试验和其他常规临床试验,以监测肾功能的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Biomolecular Techniques
Journal of Biomolecular Techniques Biochemistry, Genetics and Molecular Biology-Molecular Biology
CiteScore
2.50
自引率
0.00%
发文量
9
期刊介绍: The Journal of Biomolecular Techniques is a peer-reviewed publication issued five times a year by the Association of Biomolecular Resource Facilities. The Journal was established to promote the central role biotechnology plays in contemporary research activities, to disseminate information among biomolecular resource facilities, and to communicate the biotechnology research conducted by the Association’s Research Groups and members, as well as other investigators.
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