Extra-Renal Wilms’ Tumor in Left Lobe of Liver: A Case Report of the Rare Tumor with Review of Literature

Ajay Krishna Boralkar, Manoj Narayanrao More, Kunal Vikram Singh, Arpita Khandelwal, Aditya Abhijeet Phadke
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Abstract

Wilms tumor is the commonest childhood tumor. Extra renal Wilms' tumor is a nephroblastoma arising in locations other than kidneys. The tumor arises from misplaced metanephric blastema or is contemplated to arise from pluriotent cells. A metstasis, origin of tumor in kidneys and supernumery kidneys have to be ruled out to assign a diagnosis of extrarenal Wilms' tumor. It has been commonly reported to occur in retroperitoneum but also in inguinal region, pelvis, testis and colon. The age of occurence has been reported as Wilms; tumor in literature. It is mostly diagnosed post operatively. A preoperative biopsy combined with immunohistochemistry can help in diagnosing tumors in cases where neoadjuvant chemotherapy is anticipated. The WIlms'tumors in extrarenal location largely have favourable histology and are treated on same guidelines as Wilms' tumor. Here we present a case of extra renal Wilms' tumor arising in left lobe of liver. Liver as location for an extra renal Wilms' tumor was not found in literature.
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肝左叶肾外肾母细胞瘤1例并文献复习
肾母细胞瘤是最常见的儿童肿瘤。肾外肾母细胞瘤是一种发生在肾脏以外部位的肾母细胞瘤。肿瘤起源于错位的后肾囊胚或被认为起源于多细胞。肾外肾母细胞瘤的诊断必须排除转移、肾脏肿瘤起源和肾脏过多的可能性。它通常发生在腹膜后,但也发生在腹股沟区、骨盆、睾丸和结肠。据报道,发生年龄为Wilms;文献中的肿瘤。多数是术后诊断。术前活检结合免疫组织化学可以帮助诊断新辅助化疗的病例。外肾母细胞瘤具有良好的组织学,治疗指南与肾母细胞瘤相同。我们在此报告一例发生于肝脏左叶的肾外Wilms肿瘤。文献中未发现肝为肾外Wilms肿瘤的位置。
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