Exposure Assessment of Phthalates from House Dust and Organic Films in the Indoor Environment

J. Joen, Hyemin Lee, Seunghwan Lee, Jeong-Il Lee, C. Lee
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Abstract

ABSTRACT Background: Various types of semi-volatile organic compounds (SVOCs) exist in the public’s living environment. They occur in different forms in terms of their physical and chemical properties and partition coefficients. As a consequence, indoor exposure to SVOCs occurs via various routes, including inhalation of air and airborne particles, skin contact, and dust intake. Objectives: To propose a method for assessing human exposure to the SVOCs occurring in the air of an indoor environment, the concentrations of SVOCs in house dust and organic films measured in a real residential environment were estimated in terms of gas-phase concentration using the partition coefficient. Assessment of inhalation exposure to SVOCs was performed using this method. Methods: Phthalates were collected from samples of house dust and organic films from 110 households in a real residential environment. To perform an exposures assessment of the phthalates present in organic films, gas-phase concentration was calculated using the partition coefficient. The airborne gas-phase concentrations of phthalates from the house dust and organic films were estimated and exposure assessment was performed based on the assumption of inhalation exposure from air. Results: As a result of the exposure assessment for gas-phase phthalates from house dust and organic films, preschool children showed the highest level of inhalation of phthalates, followed by school children, adults, and adolescents. Conclusions: This study includes the limitation of not considering different SVOCs exposure pathways in the health impact assessment, including those of phthalates in the indoor living environment. However, this study has the significance of performing exposure assessment based on exposure to SVOCs present in indoor air that originated from organic films in the indoor residential environment. Therefore, the results of this study should be useful as basic data for exposure and health risk assessments of SVOCs associated with organic films in the indoor environment. ㆍ. Exposure assessment of SVOCs in the air required. ㆍ. Air phthalates were measured using house dust and organic films. ㆍ. Preschool children were the most exposed population. ㆍ. Dust and organic film could be used as a proxy for SVOC exposure via inhalation.
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室内环境中室内灰尘和有机薄膜中邻苯二甲酸盐的暴露评估
背景:在公众的生活环境中存在着多种类型的半挥发性有机化合物(SVOCs)。它们在物理、化学性质和分配系数方面以不同的形式出现。因此,通过各种途径在室内暴露于SVOCs,包括吸入空气和空气中的颗粒、皮肤接触和吸入灰尘。目的:提出一种评估人体暴露于室内环境空气中SVOCs的方法,在实际居住环境中测量的室内灰尘和有机膜中SVOCs的浓度,使用隔板系数以气相浓度估算。采用该方法对SVOCs吸入暴露进行评估。方法:对真实居住环境中110户家庭的室内粉尘和有机膜样品进行邻苯二甲酸盐采集。为了对存在于有机薄膜中的邻苯二甲酸盐进行暴露评估,气相浓度是使用分配系数来计算的。对室内灰尘和有机膜中邻苯二甲酸盐的气相浓度进行了估计,并基于空气吸入暴露的假设进行了暴露评估。结果:通过对室内灰尘和有机薄膜中邻苯二甲酸盐的暴露评估,学龄前儿童对邻苯二甲酸盐的吸入量最高,其次是学龄儿童、成人和青少年。结论:本研究存在在健康影响评估中未考虑不同SVOCs暴露途径的局限性,包括邻苯二甲酸盐在室内生活环境中的暴露途径。然而,本研究具有基于室内居住环境中源自有机薄膜的室内空气中存在的SVOCs暴露进行暴露评估的意义。因此,本研究结果可作为室内环境中与有机膜相关的SVOCs暴露和健康风险评估的基础数据。ㆍ。需要对空气中挥发性有机化合物进行暴露评估。ㆍ。空气中的邻苯二甲酸盐是用室内灰尘和有机薄膜测量的。ㆍ。学龄前儿童是受感染最多的人群。ㆍ。粉尘和有机膜可作为SVOC吸入暴露的代表。
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