Ribosome Profiling: A Useful Approach to Discover Hidden Corners of SARS-CoV-2

Milad Zandi, Emad Behboudi, Parisa Zeinali, S. Soltani, M. Shojaei
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Abstract

Following SARS-CoV-2 China epidemic in the December 2019, researches have attended to the genome of novel coronavirus. Hidden corners of SARS-CoV-2, maybe a shiny way to discover its pathogenicity and virulence. To design therapeutic agents, it is critical to map the complete repertoire of viral-translated proteins. Ribosome profiling is considered as a snapshot of all active ribosomes in a cell at a specific time point.
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核糖体分析:发现SARS-CoV-2隐藏角落的有用方法
2019年12月中国新冠肺炎疫情爆发后,人们开始关注新型冠状病毒基因组。SARS-CoV-2的隐藏角落,也许是发现其致病性和毒性的闪亮方式。为了设计治疗剂,绘制病毒翻译蛋白的完整库是至关重要的。核糖体分析被认为是在特定时间点细胞中所有活性核糖体的快照。
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