{"title":"In Silico Identification of Interaction between Ageing and Cardiovascular Disease Genes","authors":"Nikita Chordia, Teena Patidar, Priyesh Hardia","doi":"10.4172/2157-7420.1000329","DOIUrl":null,"url":null,"abstract":"Heart is the central organ that pumps pure blood to whole body through blood vessels. This circulation system involves functioning of large number of genes that interacts for proper functioning. Any malfunctioning of single gene leads to the cardiovascular diseases (CVDs) Aging is an inevitable part of life and unfortunately the risk of CVDs increases with ageing. Although numerous studies were carried on cardiovascular diseases that considered both young and aged humans, but still there are many unanswered questions as to how the genetic pathways that regulate aging influence cardiovascular disease and vice versa. Therefore, this is of great interest to identify the interaction between cardiovascular diseases and ageing genes. Genes for CVDs and ageing were collected from various databases and a network was created for their common genes. Network in analyzed to find the interaction between ageing and cardiovascular disease genes.","PeriodicalId":49032,"journal":{"name":"Journal of Medical Imaging and Health Informatics","volume":"87 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Imaging and Health Informatics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2157-7420.1000329","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Heart is the central organ that pumps pure blood to whole body through blood vessels. This circulation system involves functioning of large number of genes that interacts for proper functioning. Any malfunctioning of single gene leads to the cardiovascular diseases (CVDs) Aging is an inevitable part of life and unfortunately the risk of CVDs increases with ageing. Although numerous studies were carried on cardiovascular diseases that considered both young and aged humans, but still there are many unanswered questions as to how the genetic pathways that regulate aging influence cardiovascular disease and vice versa. Therefore, this is of great interest to identify the interaction between cardiovascular diseases and ageing genes. Genes for CVDs and ageing were collected from various databases and a network was created for their common genes. Network in analyzed to find the interaction between ageing and cardiovascular disease genes.
期刊介绍：
Journal of Medical Imaging and Health Informatics (JMIHI) is a medium to disseminate novel experimental and theoretical research results in the field of biomedicine, biology, clinical, rehabilitation engineering, medical image processing, bio-computing, D2H2, and other health related areas. As an example, the Distributed Diagnosis and Home Healthcare (D2H2) aims to improve the quality of patient care and patient wellness by transforming the delivery of healthcare from a central, hospital-based system to one that is more distributed and home-based. Different medical imaging modalities used for extraction of information from MRI, CT, ultrasound, X-ray, thermal, molecular and fusion of its techniques is the focus of this journal.
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