The different clinical scenarios of left ventricular non-compaction: report of three cases

Abstract

Abstract Introduction Left ventricular non-compaction is a morphological abnormality of exces-sive trabeculation of the left ventricle, and often, but not always, complicated by cardioembolism, arrhythmias and ventricular dysfunction. Since its irst mention in the 1980s, left ventricular non-compaction cardiomyopathy has gained increasing awareness and atten-tion. Thirty or more years of research and an ever-increasing number of published articles have improved our understanding of this rare cardiomyo-pathy, yet many issues remain unre-solved. In particular, the phenotypic and clinical expression of the same genetic cardiomyopathy assumes dif-ferent forms depending on the type of subjects involved. These case reports describe the different clinical evolu-tions of the same cardiomyopathy inde-pendently of the anatomical substrate and illustrate two aspects of the same disease in different types of patients. Case report Isolated left ventricular non-com-paction cardiomyopathy has been observed both as a sporadic and a familiar form, but newly diagnosed patients have been stratiied for symp-toms found at the time of diagnosis.