Positron Emission Tomography Myocardial Perfusion Imaging Tracer Choice for Assessment of Myocardial Blood Flow

N. Tamaki, K. Yoshinaga
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引用次数: 1

Abstract

Myocardial perfusion imaging (MPI) using positron emission tomography (PET) has high diagnostic accuracy and prognostic value in patients with known or suspected coronary artery disease (CAD). In addition, PET MPI can be used to quantify global left ventricle (LV) and regional LV myocardial blood flow (MBF) and myocardial flow reserve (MFR). Currently, there are four major PET perfusion tracers: 82 rubidium, 13 N-ammonia, 15 Owater, and 18 F-flurpiridaz. The characteristics of each tracer have been described and fully compared. Given increasing clinical needs for accurate MBF and MFR measurements, the use of PET MPI should be expanded in clinical settings in the near future.
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评价心肌血流的正电子发射断层显像示踪剂选择
使用正电子发射断层扫描(PET)进行心肌灌注成像(MPI)对已知或疑似冠状动脉疾病(CAD)的患者具有较高的诊断准确性和预后价值。此外,PET MPI可用于量化左室整体(LV)和局部左室心肌血流量(MBF)和心肌血流储备(MFR)。目前PET灌注示踪剂主要有四种:铷82种,n -氨13种,Owater 15种,氟吡唑18种。对每种示踪剂的特性进行了描述和比较。鉴于对精确MBF和MFR测量的临床需求日益增加,PET MPI的使用应在不久的将来在临床环境中扩大。
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