The present status of hyperuricemia in civil aviation flying personnel

中华航空航天医学杂志 Pub Date : 2017-03-15 DOI:10.3760/CMA.J.ISSN.1007-6239.2017.01.006

Xiaoyan Zheng

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引用次数: 1

Abstract

Objective To investigate the relationship between the level of blood uric acid and blood fat, body mass index (BMI), waist circumference, blood pressure, fatty liver disease, diabetes, urinary calculi in flying personnel of Civil Aviation Flight University of China, to search for risk factors leading to hyperuricemia, and to discuss the normal range of blood uric acid of flying personnel and prevention measures. Methods The physical examination data of 1 721 flying personnel in Civil Aviation Flight University of China were analyzed through the retrospective analysis method. According to blood uric acid level, they were divided into two groups: hyperuricemia group and control group. The comparisons on the difference of blood fat, BMI, waist circumference, and on the prevalence of hypertension, diabetes, kidney stones, fatty liver were done between two groups. Effective factors of blood uric acid were analyzed with the non-conditional Logistic regression. Results In 1 721 examined flying personnel, prevalence rate of hyperuricemia was 25.10%. BMI and waist circumference in hyperuricemia group was respectively bigger than that of control group. The triglyceride, cholesterol and LDL-C level in hyperuricemia group was respectively higher than that of control group. HDL-C in hyperuricemia group was lower than that of control group (t=2.764-7.24, P<0.01) . The percentage of drinking and fatty liver prevalence in hyperuricemia group were higher than those in control group (χ2=5.710, 7.513, P<0.05)). Abdominal obesity, hyperlipemia and drinking habit were significantly related to hyperuricemia (P<0.05). Conclusions BMI, waist circumference, the level of blood fat, drinking habit and fatty liver are related to hyperuricemia. Abdominal obesity, hyperlipidemia and drinking habit are the main risk factors which cause hyperuricemia of civil flying personnel. The preventions such as controlling the weight and the level of blood fat, as well as banning drinking would be helpful to manage the level of blood uric acid. The necessary therapy of uric acid restraining is also suggested. Key words: Hyperuricemia; Risk factors; Epidemiologic studies; Aircrews

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民航飞行人员高尿酸血症现状分析

目的调查中国民航飞行学院飞行人员血尿酸水平与血脂、体重指数(BMI)、腰围、血压、脂肪肝、糖尿病、尿路结石的关系，寻找导致高尿酸血症的危险因素，探讨飞行人员血尿酸的正常范围及预防措施。方法对中国民航飞行学院1 721名飞行人员的体检资料进行回顾性分析。根据血尿酸水平分为高尿酸血症组和对照组。比较两组患者血脂、BMI、腰围的差异，以及高血压、糖尿病、肾结石、脂肪肝的患病率。采用非条件Logistic回归分析血尿酸的影响因素。结果1 721名飞行人员高尿酸血症检出率为25.10%。高尿酸血症组BMI和腰围均大于对照组。高尿酸血症组甘油三酯、胆固醇和LDL-C水平均高于对照组。高尿酸血症组HDL-C低于对照组(t=2.764 ~ 7.24, P<0.01)。高尿酸血症组饮酒比例、脂肪肝患病率均高于对照组(χ2=5.710、7.513,P<0.05)。腹部肥胖、高脂血症、饮酒习惯与高尿酸血症显著相关(P<0.05)。结论BMI、腰围、血脂水平、饮酒习惯、脂肪肝与高尿酸血症有关。腹部肥胖、高脂血症和饮酒习惯是引起民用飞行人员高尿酸血症的主要危险因素。控制体重和血脂水平、禁止饮酒等预防措施有助于控制血尿酸水平。并提出必要的尿酸抑制治疗方法。关键词:高尿酸血症;风险因素;流行病学研究;机组人员

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来源期刊

中华航空航天医学杂志航空航天医学

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发文量

2962

期刊介绍： The aim of Chinese Journal of Aerospace Medicine is to combine theory and practice, improve and popularize, actively advocate a hundred flowers bloom and a hundred schools of thought contend, advocate seeking truth from facts, promote the development of the related disciplines of aerospace medicine and human efficiency, and promote the exchange and penetration of aerospace medicine and human efficiency with other biomedical and engineering specialties. Topics of interest for Chinese Journal of Aerospace Medicine include: -The content of the journal belongs to the discipline of special medicine and military medicine, with the characteristics of multidisciplinary synthesis and cross-penetration, and mainly reflected in the aerospace industry, aerospace flight safety and efficiency, as well as the synthesis of special medicine, preventive medicine, environmental medicine, psychology, etc. -Military aeromedicine (Air Force, Navy and Army aeromedicine) and civil aeromedicine, with a balance of aerospace medicine are the strengths of the journal. -The change in aerospace medicine from a focus on promoting physiological compensatory adaptations to enhancing human performance under extreme environmental conditions is what the journal is helping to promote. -The expansion of manuscripts in high altitude medicine is also a special emphasis of the journal.