Uterine Sarcoma With a Novel WWOX-NTRK2 Fusion in a Postmenopausal Woman With Li-Fraumeni–Like Syndrome: A Case That Expands the Spectrum of NTRK-Rearranged Uterine Tumors
Michelle Moh, Colin M. Johnson, Jennifer L. Geurts, E. Bishop
{"title":"Uterine Sarcoma With a Novel WWOX-NTRK2 Fusion in a Postmenopausal Woman With Li-Fraumeni–Like Syndrome: A Case That Expands the Spectrum of NTRK-Rearranged Uterine Tumors","authors":"Michelle Moh, Colin M. Johnson, Jennifer L. Geurts, E. Bishop","doi":"10.1097/PCR.0000000000000476","DOIUrl":null,"url":null,"abstract":"Abstract NTRK-rearranged tumors are being increasingly recognized and targeted with TRK inhibitor therapies. A novel NTRK2 fusion–positive uterine sarcoma arising in a patient with Li-Fraumeni–like syndrome is described in this article.","PeriodicalId":72144,"journal":{"name":"AJSP: reviews & reports","volume":null,"pages":null},"PeriodicalIF":0.1000,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"AJSP: reviews & reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/PCR.0000000000000476","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 3
Abstract
Abstract NTRK-rearranged tumors are being increasingly recognized and targeted with TRK inhibitor therapies. A novel NTRK2 fusion–positive uterine sarcoma arising in a patient with Li-Fraumeni–like syndrome is described in this article.