{"title":"A Model of Cerebral Blood Circulation for Future Automatic Control of Brain State","authors":"T. Utsuki","doi":"10.2316/P.2017.848-050","DOIUrl":null,"url":null,"abstract":"A static model of cerebral blood circulation is constructed for developing an automatic control system of physiological brain state, which will be used in brain resuscitation. In this paper, the constructed model was partially verified in the simulation using the actual data of a 70 years old patient with stenosis at left internal carotid artery. In the simulation, each arterial blood flow in cerebral blood circulation were calculated and were compared with the actual data measured by MRI and SPECT. In addition, the distribution of blood pressure in the Circle of Willis and the change of blood pressure along blood flow were also calculated for verifying against physiological knowledge. These results indicated that this model can represent the arterial part of cerebral blood circulation of this patient. And, the results also indicate the possibility that a static model such as our model represents cerebral blood circulation sufficiently. Thus, the construction of our model is enough significant.","PeriodicalId":49801,"journal":{"name":"Modeling Identification and Control","volume":"13 1","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modeling Identification and Control","FirstCategoryId":"94","ListUrlMain":"https://doi.org/10.2316/P.2017.848-050","RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"AUTOMATION & CONTROL SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
A static model of cerebral blood circulation is constructed for developing an automatic control system of physiological brain state, which will be used in brain resuscitation. In this paper, the constructed model was partially verified in the simulation using the actual data of a 70 years old patient with stenosis at left internal carotid artery. In the simulation, each arterial blood flow in cerebral blood circulation were calculated and were compared with the actual data measured by MRI and SPECT. In addition, the distribution of blood pressure in the Circle of Willis and the change of blood pressure along blood flow were also calculated for verifying against physiological knowledge. These results indicated that this model can represent the arterial part of cerebral blood circulation of this patient. And, the results also indicate the possibility that a static model such as our model represents cerebral blood circulation sufficiently. Thus, the construction of our model is enough significant.
期刊介绍：
The aim of MIC is to present Nordic research activities in the field of modeling, identification and control to the international scientific community. Historically, the articles published in MIC presented the results of research carried out in Norway, or sponsored primarily by a Norwegian institution. Since 2009 the journal also accepts papers from the other Nordic countries.
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