A Case Report of Conus Medullaris Tumor Causing a Diagnostic Dilemma

I. Chakraborty
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Abstract

Intramedullary astrocytomas of the spinal cord are rarer than intracranial astrocytomas. Glioblastoma Multiforme (GBM) generally does not involve the spinal cord (1-5% of all GBM cases) and presents as only 1.5% of all spinal cord tumors. The ratio of low-grade to high-grade astrocytomas in the spinal cord is about 3:1. Case Report: We report a case of a 40-year-old male patient complaining of back pain. Insidious in onset, gradual in progression, deep-seated since 8 months. Walking has been difficult for 6 months due to associated foot drop in the left lower limb. There was no evidence of bowel or bladder involvement, and there were no complaints in the upper limbs or elsewhere. On examination, the motor system showed foot drop and EHL weakness in the left lower limb. Following that, he underwent D12-L1 laminectomy with subtotal excision of the lesion under neuromonitoring. Glioma was discovered on histopathology. Adjuvant radiation and chemotherapy were given. Conclusion: The rarity of this entity may have hampered the development of standardized regimens for optimal treatment. We believe that accumulated experience in the treatment of this lethal condition might contribute well to improving its therapeutic outcome.
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髓圆锥肿瘤致诊断困境1例报告
脊髓髓内星形细胞瘤较颅内星形细胞瘤少见。多形性胶质母细胞瘤(GBM)通常不累及脊髓(占所有GBM病例的1-5%),仅占所有脊髓肿瘤的1.5%。脊髓中低级别星形细胞瘤与高级别星形细胞瘤的比例约为3:1。病例报告:我们报告一个病例40岁的男性病人抱怨背部疼痛。起病隐匿,进展缓慢,8个月以来已根深蒂固。由于左下肢足部下垂,行走困难已达6个月。没有证据表明肠或膀胱受累,上肢或其他部位没有症状。运动系统检查显示左下肢足下垂和EHL无力。随后,在神经监测下行D12-L1椎板切除术,病灶次全切除。组织病理学发现胶质瘤。给予辅助放疗和化疗。结论:该实体的稀缺性可能阻碍了最佳治疗的标准化方案的发展。我们相信,在治疗这种致命疾病方面积累的经验可能有助于改善其治疗效果。
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