保存剤を含有していない0.125%チロキサポール吸入液における一回量包装の有用性

Abstract

By comparing the usual method of measuring medication dosage in medical cups in our hospital (A packages) with newly developed one dose packages (B, C packages) the stability of the ingredients, the sterility of the material, and the accuracy of the correctness of the measuring the samples, we assessed the usefulness of one dose packages of preservativefree 0.125% tyloxapol solutions for the administration of oral medications. The results were as follows: 1) pH tended to rise in A as the strage temperature increased but was stable in both B and C. No changes in the external appearance were detectable in any of them. 2) No microbial contamination was found in any of the packages, A, B or C. 3) The measuring accuracy was better in B and C than in A. Thus, the one dose packages appeared to be more useful than the usual method of measuring drugs using medical cups as a method by which 0.125% tyloxapol solutions for inhalations can be used safely and conveniently even when supplied to patients.