Breast Cancer Treatment Protocols: Systematic Review of the Last 35 Years

Abstract

Breast cancer is the main leading type of cancer for women around the world and is responsible for 522,000 deaths per year worldwide. In order to reduce this number, clinicians and researchers are always looking for new strategies and protocols. However, the treatment for breast cancer is challenging and requires as much information as possible. To this end, we conducted a review of all protocols used for breast cancer treatment in the last 35 years with the objective to help clinicians to choose the best treatment possible available in their region. Many of the protocols are international references, and for that reason have been used in many countries like USA and Europe. The data, depicted in tables, may be helpful for clinicians worldwide and researchers to better understand the evolution of breast cancer protocols such as helping make daily routine decisions.