What Is Your Diagnosis?

S. Kavusi, V. Lajevardi, F. Moinedin, M. Barzegar
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Abstract

A 40–year-old woman referred to the dermatological clinic of Razi hospital with painful lesions on the axillae, between her breasts and intergluteal region since adolescence. The patient had been treated with a variety of antibiotics with only minimal improvement. The lesions reappeared with cessation of treatments. On cutaneous examination, multiple furuncle-like discharging nodules were observed over the axillae, between the breasts, buttock and gluteal region (figure 1). Other findings were giant black comedones and depressed scars which were found between the aforementioned lesions, particularly on her back (figure 2). A number of pits with 2 to 3 mm diameter were seen around the mouth (figure 3). Additionally, there were hyperpigmented macules in a reticular pattern over the axillae, inframammary area and groin (figure 4). Mucosal surfaces and nails were not pigmented. Systemic examination was normal. Laboratory data were all within normal limits. In familial history, one of her sisters, aged 50 years, had a similar pattern of pigmentation from the age of 20.
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一名40岁妇女自青春期以来因腋窝、乳房之间和臀间区疼痛病变转介至Razi医院皮肤科诊所。病人曾接受多种抗生素治疗,但改善甚微。停止治疗后病变再次出现。在皮肤检查中,在腋窝、乳房、臀部和臀区之间观察到多个疖状排出性结节(图1)。在上述病变之间,特别是在她的背部(图2),其他发现是巨大的黑色粉刺和凹陷疤痕(图2)。口周围可见许多直径为2至3mm的凹坑(图3)。此外,在腋窝上方有网状的色素沉着斑。乳下区和腹股沟(图4)。粘膜表面和指甲未见色素沉着。全身检查正常。实验室数据均在正常范围内。在家族病史中,她的一个50岁的姐妹从20岁开始就有类似的色素沉着模式。
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