Sequential bronchoplastic lobectomies in complex treatment for synchronous bilateral multiple primary non-small cell lung cancer: a rare clinical case

O. Kit, D. Kharagezov, Y. Lazutin, E. Mirzoyan, I. Leyman, S. N. Tikhonova
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Abstract

Today, lung cancer (LC) occupies a special place in the oncological general morbidity among the male population both in Russia and in foreign countries. Despite modern diagnostic capabilities provided for modern physicians, steadily frequent cases of triggering and exclusion are more common in patients older than 60–65 years. Surgery is the main treatment for early-stage non-small cell lung cancer (NSCLC), but as the disease progresses, unfortunately, its effectiveness decreases. The strategy of diagnosing and treating patients with one NSCLC has been developed and worked out for a long time and does not cause any difficulties, but in the presence of two or more tumors, especially when they are located in both lungs, the correct choice of therapy is determined by many additional factors. This article describes the rare use of extended bronchoplastic upper lobectomy as a surgical component of the complex treatment of a patient with bilateral synchronous NSCLC. Based on our own observational data, it can be claimed that the use of modern therapeutic principles in combination with surgical intervention allows achieving satisfactory long-term results in the treatment of patients with primary multiple NSCLC.The interest of the presented observation is based on the fact that it contains a description of a rare and unique application of sequential extended bronchoplastic upper lobectomy as a surgical component of the complex treatment of a patient with bilateral synchronous NSCLC, which we have not found analogues in the literature. We have shown that the consistent use of modern therapeutic modalities makes it possible to achieve satisfactory long-term results in the treatment of a locally advanced disease. 
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序贯支气管增生性肺叶切除术治疗双侧多发原发非小细胞肺癌一例罕见临床病例
今天,肺癌(LC)在俄罗斯和国外男性人口的肿瘤一般发病率中占有特殊的地位。尽管现代医生提供了现代诊断能力,但在60-65岁以上的患者中,触发和排除的病例更为常见。手术是早期非小细胞肺癌(NSCLC)的主要治疗方法,但不幸的是,随着疾病的进展,手术的效果会下降。诊断和治疗单一NSCLC患者的策略已经发展和完善了很长时间,并没有造成任何困难,但在存在两个或更多肿瘤的情况下,特别是当它们位于双肺时,正确的治疗选择取决于许多其他因素。这篇文章描述了罕见的扩大支气管增塑型上肺叶切除术作为双侧同步性非小细胞肺癌患者复杂治疗的手术组成部分。根据我们自己的观察数据,可以声称,采用现代治疗原则结合手术干预,可以在原发性多发性NSCLC患者的治疗中取得满意的长期效果。所提出的观察的兴趣是基于这样一个事实,即它包含了一种罕见而独特的应用,即顺序延长支气管增长性上肺叶切除术作为双侧同步非小细胞肺癌患者复杂治疗的手术组成部分,我们在文献中没有发现类似的情况。我们已经表明,持续使用现代治疗方式可以在局部晚期疾病的治疗中取得令人满意的长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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