Synthesis, Characterization and Antioxidant Activity of Novel 3-(2,5-dioxo-imidazolidin-1-yl)-1,1-diethylurea Derivatives

H. N. Deepakumari, M. Raghu, C. Kumar
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Abstract

: A novel class of hydantoin derivatives was synthesized and their antioxidant activity was evaluated. The newly synthesized compounds were characterized using 1 H NMR, IR, Mass spectra and elemental analysis. The antioxidant activity of synthesized compounds ( 3a-d ) were examined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide hydroxyl radical scavenging assay. It is revealed from the antioxidant screening results that the compounds 3a and 3d manifested profound antioxidant potential.
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新型3-(2,5-二氧基咪唑烷-1-基)-1,1-二乙基脲衍生物的合成、表征及抗氧化活性研究
合成了一类新的海因衍生物,并对其抗氧化活性进行了评价。用1h NMR、IR、质谱和元素分析对新合成的化合物进行了表征。合成的化合物(3a-d)通过2,2-二苯基-1-苦味酰肼(DPPH)、一氧化氮羟基自由基清除实验检测其抗氧化活性。抗氧化筛选结果表明,化合物3a和3d具有较强的抗氧化潜力。
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