Rationale for Translational Research on Targeted Alpha Therapy in Japan —Renaissance of Radiopharmaceuticals Utilizing Astatine-211 and Actinium-225—

Radioisotopes Pub Date : 2020-10-15 DOI:10.3769/radioisotopes.69.329

T. Yano, 矢野恒夫, K. Hasegawa, 長谷川功紀, Tatsuhiko Sato, 佐藤達彦, M. Tatsumi, 巽光朗, T. Watabe, 渡部直史, Yuichiro Kadonaga, 角永悠一郎, K. Kabayama, 樺山一哉, K. Fukase, 深瀬浩一, A. Hachisuka, 蜂須賀暁子, Y. Hirabayashi, 平林容子, H. Fujii, 藤井博史, Y. Yonekura, 米倉義晴

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Abstract

1 QiSS-Targeted Alpha Therapy Research, Research Center for Nuclear Physics, Osaka University, 2 Center for Instrumental Analysis, Kyoto Pharmaceutical University, 3 Nuclear Science and Engineering Center, Japan Atomic Energy Agency, 4 Department of Radiology, Osaka University Hospital, 5 Department of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 6 Institute for Radiation Sciences, Osaka University, 7 Department of Chemistry, Graduate School of Science, Osaka University, 8 Division of Biochemistry, National Institute of Health Sciences, 9 Center for Biological Safety & Research, National Institute of Health Sciences, 10 Division of Functional Imaging, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center † fam-yano@tcct.zaq.ne.jp

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日本靶向α治疗转化研究的基本原理——利用astatin -211和Actinium-225 -的放射性药物的复兴

1大阪大学核物理研究中心qiss靶向α治疗研究，2京都药科大学仪器分析中心，3日本原子能机构核科学与工程中心，4大阪大学医院放射科，5大阪大学医学研究生院核医学与示踪动力学学系，6大阪大学放射科学研究所，7科学研究生院化学系，大阪大学，8国立健康科学研究所生物化学学部，9国立健康科学研究所生物安全与研究中心，10功能成像学部，国立癌症中心探索性肿瘤研究与临床试验中心†fam-yano@tcct.zaq.ne.jp

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