Severe Acute Respiratory Syndrome – Coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19): An overview of Structure, Clinical Features, Diagnosis and Treatment

Abstract

Coronavirus disease-2019 (COVID-19) has spread globally since its discovery in Hubei province, China in December 2019. It has already been announced as a pandemic disease by world health organization (WHO). This disease is caused by severe acute respiratory syndrome corona virus-2 (SARS-CoV-2), which is an enveloped RNA virus and highly contagious. This is a new coronavirus, still changing, and put the scientific authority in a puzzle. The fatality rate of COVID-19 is higher compared to other coronavirus diseases such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). The outbreak of COVID-19 has created a severe threat to public health across the world. In this review, we render an overview of COVID-19 disease such as origin and pathogenesis of SARS-CoV-2, clinical manifestations along with complications, diagnosis and treatment actions as well as preventive measures to control viral transmission.