Limb Salvage through Intermediary Wound Coverage with Acellular Dermal Matrix Template after Persistent Pseudomonas Aeruginosa Infection in a Burn Patient.

IF 1 Q4 CRITICAL CARE MEDICINE European burn journal Pub Date : 2022-01-12 DOI:10.3390/ebj3010004
Mateusz Gładysz, Vincent März, Stefan Ruemke, Evgenii Rubalskii, Peter Maria Vogt, Nicco Krezdorn
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Abstract

Secondary infections of skin grafts pose a continuous problem in burn patients, very often leading to loss of transplanted skin grafts and making multiple surgical revisions necessary. We present a case report about persisting Pseudomonas aeruginosa infection in burn patients with known diabetes. The burn wounds in lower extremities required repeated debridements, multiple skin grafting attempts and finally an application of the dermal scaffold NovoSorb BTM. With these measures, we managed to undertake a successful reconstruction of infected burn defects and pre-vent an amputation. We concluded that the NovoSorb BTM could be seen as an additional promising tool in a burn surgery armamentarium. In cases where radical surgical wound decontamination is not possible without risking the loss of the limb, the application of NovoSorb BTM over a contaminated field can win extra time for topical infection treatment and additionally provide an excellent skin grafting ground.

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烧伤患者持续感染绿脓杆菌后,通过使用细胞真皮基质模板进行中间伤口覆盖挽救肢体。
皮肤移植的继发感染是烧伤患者的一个持续性问题,通常会导致移植皮肤的缺失,并使多次手术翻修成为必要。我们报告了一例已知患有糖尿病的烧伤患者持续感染铜绿假单胞菌的病例。患者的下肢烧伤创面需要反复清创、多次植皮,最后才使用真皮支架 NovoSorb BTM。通过这些措施,我们成功地重建了感染性烧伤缺损,并避免了截肢。我们的结论是,NovoSorb BTM 可以被视为烧伤外科手术武器库中的另一种有前途的工具。在不冒失去肢体风险的情况下不可能对伤口进行彻底的手术清创时,在受污染的创面上使用 NovoSorb BTM 可以为局部感染治疗赢得更多的时间,同时还能为植皮提供良好的条件。
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