Small Cell Neuroendocrine Carcinoma of the Endometrium: Literature Review

Abstract

The article was prepared with the consent of the patient. We obtained the informed consent form from the patient. A 48-year-old perimenopausal woman presented to our gynecology outpatient clinic with vaginal bleeding and abdominal pain. In the routine biochemical study, fasting blood glucose was found to be 169.8 mg/dL, WBC 21.77 10^3/uL, CRP <2.00 mg/L, and HCT 40.3%. Since no clear pathology was detected in abdominal ultrasonography, endometrial curettage was performed for diagnostic purposes, which revealed a malignant epithelial tumor as pathological diagnosis. Afterwards, surgical treatment was planned and radical hysterectomy-bilateral salpingo-oopherectomypelvic and paraaortic lymphadenectomy was performed. Macroscopically, a malignant mass of 6.7x2 cm in size was found in the lower uterine segment. The microscopic study revealed a tumor with poorly differentiated small round cells located in the lower uterine segment-endometrium and associated with the cervical intraepithelial carcinoma. Tumor cells were present in the endometrium, endometrial polyp, and cervical stroma. However, they were not observed in cervical glands, fallopian tubes, and ovaries. Turkiye Klinikleri J Case Rep. 2020;28(2):99-102