The efficiency and safety of a dietary supplement used in the treatment of preschool and school children with acute respiratory infections

L. Sagić, K. Milosevic, O. Ostojić, A. Agić
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Abstract

Introduction. The aim of this research was to assess the efficiency and safety of a natural product N-acetylcysteine and propolis in the children with acute respiratory infections with increased mucus production and cough. Material and Methods. The research was conducted in the period April 2016 - February 2017 among 145 pediatric patients aged 3 to 14 years with symptoms of acute respiratory infection. They were divided into two groups. Group A - preschool and Group B - school children. The first clinical examination included demographic data, physical examination. filling out the quality of cough questionnaire, and taking nasal and pharyngeal swabs. After a ten-day therapy, physical examination was conducted, quality of cough questionnaire was refilled and swabs were taken. Results. Group A included 73 and Group B 72 children. No statistically significant difference was observed in the incidence of respiratory disease episodes. In Group B children received antibiotics less often. started school at an early age and more children had daily activities in regard to children in Group A. Statistically, both groups of children coughed early in the morning more than during the day. The results of control swab tests were negative in both groups. No side effects were reported in either group. Conclusion. The propolis combined with N-acetylcysteine in a pediatric syrup is a good choice in the treatment of acute respiratory infections in children with accompanied mucus production and cough. The product is efficient and safe for all age groups.
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一种膳食补充剂用于治疗学龄前和学龄儿童急性呼吸道感染的有效性和安全性
介绍。本研究的目的是评估天然产物n -乙酰半胱氨酸和蜂胶在患有急性呼吸道感染的儿童中产生粘液和咳嗽的效率和安全性。材料和方法。该研究于2016年4月至2017年2月期间对145名3至14岁的急性呼吸道感染症状的儿童患者进行了研究。他们被分成两组。A组是学龄前儿童,B组是学龄儿童。第一次临床检查包括人口统计资料、体格检查。填写咳嗽质量调查问卷,取鼻咽拭子。治疗10 d后,进行体格检查,填写咳嗽质量问卷并取拭子。结果。A组73例,B组72例。呼吸系统疾病发作的发生率无统计学差异。B组儿童较少使用抗生素。与a组的孩子相比,a组的孩子更早开始上学,并且有更多的孩子参加日常活动。统计数据显示,两组孩子在清晨咳嗽的次数都比白天多。对照组拭子试验结果均为阴性。两组均无副作用报告。结论。小儿糖浆中蜂胶联合n -乙酰半胱氨酸是治疗伴有黏液产生和咳嗽的儿童急性呼吸道感染的良好选择。该产品对所有年龄组都有效且安全。
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