Drugs In Pipeline For Type-2 Diabetes

R. Mahajan, K. Gupta
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引用次数: 7

Abstract

Hyperglycemia, obesity, insulin resistance, dyslipidemia and hypertension are interrelated cardiometabolic risk factors for the development of type-2 diabetes and metabolic syndrome. Prevalence of type-2 diabetes is growing at an alarming rate. Treatment target for type-2 diabetes is to keep daily glucose profile as close as possible to that of a non-diabetic person. Sulfonylureas, thiazolidinediones, meglitinides, biguanides and acarbose inhibitors are already being used in controlling glucose levels in type-2 diabetes. This review discusses the new drugs with novel mechanism of actions; which are in pipeline and were marketed recently or will be in market in near future.
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2型糖尿病药物上市
高血糖、肥胖、胰岛素抵抗、血脂异常和高血压是发生2型糖尿病和代谢综合征的相关心脏代谢危险因素。2型糖尿病的患病率正以惊人的速度增长。2型糖尿病的治疗目标是保持每日血糖水平尽可能接近非糖尿病患者。磺脲类药物、噻唑烷二酮类药物、美格列酮类药物、双胍类药物和阿卡波糖抑制剂已被用于控制2型糖尿病患者的血糖水平。本文综述了具有新的作用机制的新药;这些产品正在筹备中,最近已经上市或将在不久的将来上市。
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