"Evaluation of the Effect of a Mobile Phone Application on Treatment Success and Drug Adherence in Hypertensive Patients"

Mert Kaşkal
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Abstract

Evaluation of the Effect of a Mo bile Phone Application on Treatment Suc cess and Drug Adherence in Hypertensive Patients. One of the most important factors affecting the prognosis of hypertension is the patients’ adherence to drug therapy. In this study, it was aimed to evaluate the improvement in drug adherence in hypertensive patients after using a mobile phone application. Patients and Methods: In this single-centered study fifty patients with hypertension were recruited. All the patients used the Medisafe® mobile phone application for 8 weeks. The application is intended to increase drug adherence of patients and provide better blood pressure control. The differences in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels from the baseline and the levels at the end of the study were compared. The drug adherence was evaluated using the 8-question Morisky Drug Adherence Scale (MMAS-8) at baseline and at the end of the study. Results: The mobile application utilization provided a significant decrease in both the mean SBP levels by 6.2 mmHg (p<0,001) and in the mean DBP levels by 2.4 mmHg (p=0.035) Additionally, the mobile application also positively and significantly increased the drug adherence of the patients (mean baseline score: 5.54 vs mean end of the study score:6.3 and p=0,001). In the subgroup analysis of the study demonstrated that in addition to an increase in patients drug adherence, the use of the mobile application provided a significant decrease in the mean SBP levels by 6.6 mmHg(p=0.016) in geriatric patients but the decrease in DBP did not significantly change (p>0.05). In geriatric patients, the mean difference between drug adherence scores baseline and after application was found to be significant (p=0.006). With the use of mobile application, patients with polypharmacy had decreased mean SBP and DBP levels, and an increased mean MMAS-8 score of 5.07 to 5.85 (p=0.009). The present pilot study demonstrated that mobile application use in patients with hypertension may increase the treatment success and the patients drug adherence. The beneficial effects of mobile applications in the treatment of hypertension and other common chronic diseases should be evaluated in further larger clinical trials.
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《手机应用对高血压患者治疗成功及药物依从性的影响评价》
手机应用对高血压患者治疗成功率及药物依从性的影响评价。影响高血压预后的重要因素之一是患者对药物治疗的依从性。本研究旨在评估使用手机应用程序后高血压患者药物依从性的改善情况。患者和方法:在这项单中心研究中,招募了50例高血压患者。所有患者使用Medisafe®手机应用程序8周。该应用程序旨在增加患者的药物依从性,并提供更好的血压控制。比较基线和研究结束时收缩压(SBP)和舒张压(DBP)水平的差异。在基线和研究结束时使用8题莫里斯基药物依从性量表(MMAS-8)评估药物依从性。结果:移动应用程序的使用使两组患者的平均收缩压水平显著降低6.2 mmHg (p0.05)。在老年患者中,药物依从性评分基线和用药后的平均差异有统计学意义(p=0.006)。使用移动应用程序后,多药患者的平均收缩压和舒张压水平下降,平均MMAS-8评分升高,为5.07 ~ 5.85 (p=0.009)。目前的初步研究表明,在高血压患者中使用移动应用程序可以提高治疗成功率和患者的药物依从性。移动应用程序在治疗高血压和其他常见慢性病方面的有益效果应在更大规模的临床试验中进行评估。
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