Thermal Therapy as Multidisciplinary Therapy Applied to Rectal Cancer:: A New Perspective and Potential Role of This Treatment

Abstract

: To avoid colostomy, we try to improve local control, i e . to perform pathological complete response (pCR) by the neoadjuvant chemoradiation (NACR) with concurrent thermal therapy, falling into a so-called “ wait-and-see policy ” . The aim of this study is examined whether the treatment response of NACR with concurrent thermal therapy for rectal cancer can be predicted after the treatment completion and we showed the changing history of our treatment protocol, current results of our study and a new perspective and potential role of thermal therapeutic approaches in patients with rectal cancer. In this study, 81 patients with rectal cancers (54 resected, M : F ＝ 61 : difference RO ≥ 0 Watt group (p ＜ 0.05), but not in the difference RO ＜ 0 Watt group. These data suggest that patients with a small tumor ( GTV ≤ 32 cm 3 ) and a difference RO ＜ 0 Watt are enough to treat by NACR only and those with a large tumor ( GTV ≥ 80 cm 3 ) and a RO difference ≥ 0 Watt by NACR with concurrent with thermal therapy.