V. Dženkevičiūtė, Agnė Skujaitė, E. Rinkūnienė, Ž. Petrulionienė, L. Gumbiene, Sandra Katkiene, A. Laucevičius
{"title":"Pregnancy-related severe hypertriglyceridemia","authors":"V. Dženkevičiūtė, Agnė Skujaitė, E. Rinkūnienė, Ž. Petrulionienė, L. Gumbiene, Sandra Katkiene, A. Laucevičius","doi":"10.2217/clp.15.25","DOIUrl":null,"url":null,"abstract":"Abstract The increase in plasma triglyceride level in pregnancy is modest, but in those who have deficiencies in lipoprotein lipase or apolipoprotein C-II (i.e., familial hyperlipidemia), the increase in very LDL concentration cannot be controlled and results in severe hypertriglyceridemia. This case is related to severe primary hypertriglyceridemia (types V) detected on the 25th week of gestation and treated with regular therapeutic plasma exchange and later on with alternate plasmapheresis with donated plasma. No complications were observed. A healthy male baby was delivered on the 39th week of pregnancy. After giving birth, the maternal triglyceride levels showed a remarkable reduction.","PeriodicalId":55252,"journal":{"name":"Clinical Lipidology","volume":"33 1","pages":"299 - 304"},"PeriodicalIF":0.0000,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Lipidology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/clp.15.25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 3
Abstract
Abstract The increase in plasma triglyceride level in pregnancy is modest, but in those who have deficiencies in lipoprotein lipase or apolipoprotein C-II (i.e., familial hyperlipidemia), the increase in very LDL concentration cannot be controlled and results in severe hypertriglyceridemia. This case is related to severe primary hypertriglyceridemia (types V) detected on the 25th week of gestation and treated with regular therapeutic plasma exchange and later on with alternate plasmapheresis with donated plasma. No complications were observed. A healthy male baby was delivered on the 39th week of pregnancy. After giving birth, the maternal triglyceride levels showed a remarkable reduction.
期刊介绍:
The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.