Identification of Protoceratium reticulatum as the biogenetic origin of yessotoxin.

Natural toxins Pub Date : 1998-12-07 DOI:10.1002/19970504NT7
M. Satake, L. Mackenzie, T. Yasumoto
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引用次数: 263

Abstract

Yessotoxin (YTX), a disulfated polyether toxin, was isolated from cultured cells of the marine dinoflagellate Protoceratium reticulatum and unambiguously identified by high-performance liquid chromatography, 1H NMR, and MS data. The result is the first to confirm toxigenicity of this species and demonstrate it as one of the biogenetic origins of YTX found in shellfish.
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网纹原虫yessotoxin生物起源的鉴定。
Yessotoxin (YTX)是一种二硫聚醚毒素,从海洋鞭毛藻Protoceratium reticulatum培养细胞中分离得到,并通过高效液相色谱、1H NMR和MS数据进行了明确鉴定。该结果首次证实了该物种的毒性,并证明它是贝类中发现的YTX的生物遗传学起源之一。
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Erratum: Alfonso D, Johnson HA, Colman-Saizarbitoria T, Presley CP, McCabe GP, McLaughlin JL (1996): SARs of annonaceous acetogenins in rat liver mitochondria. Nat Toxins 4:181-188. Advances in detection methods for fungal and algal toxins. HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. Neuronal binding of tetanus toxin compared to its ganglioside binding fragment (H(c)). A new type sandwich immunoassay for microcystin: production of monoclonal antibodies specific to the immune complex formed by microcystin and an anti-microcystin monoclonal antibody.
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