Specialists Create 3D Tissue Models of Mind Tumors in A Cerebrum Copying Microenvironment

U. Sowmya
{"title":"Specialists Create 3D Tissue Models of Mind Tumors in A Cerebrum Copying Microenvironment","authors":"U. Sowmya","doi":"10.37421/.JTSE.2020.11.231","DOIUrl":null,"url":null,"abstract":"A group of Tufts College drove specialists has created three-dimensional (3D) human tissue culture models of pediatric and grown-up mind malignant growths in a cerebrum mirroring microenvironment, a noteworthy progression for the investigation of cerebrum tumor science and pharmacological reaction. The investigation was distributed today in Nature Correspondences. The scientists made models that incorporate cerebrum inferred extracellular grid (ECM) - the mind boggling system of proteins and amino acids with bound sugars normally found in the mind. The ECM offers help for encompassing neural tissue, yet additionally assists with managing cell development and advancement. Adjustments in ECM structure have been related with mind tumor movement, which thusly changes examples of hereditary and protein articulation in the tumor cells.","PeriodicalId":17539,"journal":{"name":"Journal of Tissue Science and Engineering","volume":"33 1","pages":"1-1"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Tissue Science and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37421/.JTSE.2020.11.231","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

A group of Tufts College drove specialists has created three-dimensional (3D) human tissue culture models of pediatric and grown-up mind malignant growths in a cerebrum mirroring microenvironment, a noteworthy progression for the investigation of cerebrum tumor science and pharmacological reaction. The investigation was distributed today in Nature Correspondences. The scientists made models that incorporate cerebrum inferred extracellular grid (ECM) - the mind boggling system of proteins and amino acids with bound sugars normally found in the mind. The ECM offers help for encompassing neural tissue, yet additionally assists with managing cell development and advancement. Adjustments in ECM structure have been related with mind tumor movement, which thusly changes examples of hereditary and protein articulation in the tumor cells.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
专家在大脑复制微环境中创建大脑肿瘤的三维组织模型
一组塔夫茨学院的专家已经在大脑镜像微环境中创建了儿童和成人大脑恶性肿瘤生长的三维(3D)人体组织培养模型,这是研究大脑肿瘤科学和药理反应的一个值得注意的进展。这项调查今天发表在《自然通讯》上。科学家们制作了包含大脑推断的细胞外网格(ECM)的模型,这是一种令人难以置信的系统,由蛋白质和氨基酸与通常在大脑中发现的结合糖组成。ECM提供了包围神经组织的帮助,但也有助于管理细胞的发育和进步。ECM结构的调整与脑瘤运动有关,从而改变了肿瘤细胞中的遗传和蛋白质衔接。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Development and Evolution of Cartilage Tissues and itandrsquo;s Properties Sub-Atomic Science of Cells Number of Stages in 3D Bio-Printing of Living Tissues Biomedical Designing Discipline that Utilizes a Blend of Cells Impacts of Openness to Electromagnetic Field on Rats
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1