Role of Candida Species in Oral Lichen Planus

N. Swain, Shilpa Patel, Jigna Pathak, Priyadarshani R Sarkate, Rashmi Maruti Hosalkar, N. Sahu
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Abstract

Candida albicans is the most common fungal pathogen in humans, although other Candida species can also cause candidiasis. Patients with symptomatic or erythematous oral lichen planus (OLP) have commonly been associated with these. In recent times, however, there has been a notable shift in the incidence of non-Candida albicans (NCA) species which is gaining prominence due to significant differences in their susceptibility to antimycotic drugs. Studies showed that C. glabrata and C. tropicalis were the most common NCA species isolated in OLP. Treatment failure is common among NCA species in OLP due to its intrinsic resistant or low susceptibility to commonly used antifungal agents. This article reviews the role of Candida species in etiology, pathogenesis, clinical features, diagnosis, and management of OLP. How to cite this article: Sarkate PR, Pathak J, Patel S, et al. Role of Candida Species in Oral Lichen Planus. J Contemp Dent 2019;9(3):124–129.
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念珠菌在口腔扁平苔藓中的作用
白色念珠菌是人类最常见的真菌病原体,尽管其他种类的念珠菌也可引起念珠菌病。有症状或红斑性口腔扁平苔藓(OLP)的患者通常与这些有关。然而,近年来,非白色念珠菌(NCA)物种的发病率发生了显著变化,由于它们对抗真菌药物的易感性存在显著差异,这种变化正日益突出。研究表明,glabrata和C. tropical是OLP中最常见的NCA物种。治疗失败在OLP的NCA物种中很常见,因为它们对常用的抗真菌药物具有固有的抗性或低易感性。本文综述念珠菌在OLP的病因、发病机制、临床特征、诊断和治疗中的作用。如何引用本文:Sarkate PR, Pathak J, Patel S等。念珠菌在口腔扁平苔藓中的作用。现代医学学报,2019;9(3):124-129。
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