Lowering LDL-C with alirocumab, an investigational PCSK9 inhibitor

Q Medicine Clinical Lipidology Pub Date : 2014-12-01 DOI:10.2217/clp.14.55
J. Edelberg
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Abstract

Jay Edelberg is an MD PhD graduate of Duke University in Durham, North Carolina, USA and trained in clinical cardiology at the Beth Israel Deaconess Medical Center in Boston. From 1999 to 2006, Dr Edelberg served as CCU cardiologist and led the Cardiac Vascular Biology Research Laboratory at Weill-Cornell Medical Center, with a specific research focus on cardiovascular stem cells and biomarkers of cardiac aging. In 2006, Dr Edelberg became Director of Cardiovascular Urogenital Biomarker research at GlaxoSmithKline. Two years later, he moved to Bristol-Myers Squibb and progressed to become the US medical lead for Eliquis (apixaban). He joined Sanofi in 2012 as Vice President and Head of the newly formed PCSK9 Development & Launch Unit, reporting to Elias Zerhouni, President, Global R&D and Hanspeter Spek, President, Global Operations, Sanofi. Over the years, Dr Edelberg has published more than 75 peer-reviewed publications and has participated in numerous research and peer-review committees, including those of the National Institutes of Health (NIH), American Heart Association (AHA) and the California Institute for Regenerative Medicine (CIRM). He currently sits on the American Federation for Aging Research Board of Directors and is a Section Editor for the journal Aging Cell.
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alirocumab降低LDL-C,一种实验性PCSK9抑制剂
Jay Edelberg博士毕业于美国北卡罗来纳州达勒姆的杜克大学,曾在波士顿Beth Israel Deaconess医疗中心接受临床心脏病学培训。从1999年到2006年,Edelberg博士担任CCU心脏病专家,并领导威尔-康奈尔医学中心的心血管生物学研究实验室,专门研究心血管干细胞和心脏衰老的生物标志物。2006年,Edelberg博士成为葛兰素史克(GlaxoSmithKline)心血管泌尿生殖生物标志物研究主任。两年后,他跳槽到百时美施贵宝(Bristol-Myers Squibb),并成为Eliquis(阿哌沙班)的美国医学负责人。他于2012年加入赛诺菲,担任新成立的PCSK9开发和发布部门的副总裁兼主管,向赛诺菲全球研发总裁Elias Zerhouni和全球运营总裁Hanspeter Spek汇报。多年来,Edelberg博士发表了超过75篇同行评议的出版物,并参加了许多研究和同行评议委员会,包括美国国立卫生研究院(NIH)、美国心脏协会(AHA)和加州再生医学研究所(CIRM)。他目前是美国老龄化研究委员会的成员,也是《衰老细胞》杂志的编辑。
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来源期刊
Clinical Lipidology
Clinical Lipidology 生物-生化与分子生物学
CiteScore
0.44
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.
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