{"title":"Resting State Analysis: Simulation and validation of RS-fMRI dataset for ADHD Subjects","authors":"P. Prasanth, O. Maheswari","doi":"10.37896/pd91.4/91475","DOIUrl":null,"url":null,"abstract":"Novel methods for the analysis of functional magnetic resonance imaging (fMRI) data are being reported lately. It is necessary to validate these methods for reliability as the interpretations of the results are subjective as the ground truth in the fMRI data is not known. Validation of analysis methods requires knowledge of the ground truth of the data. Simulation studies are necessary to assess the quality of the statistical technique/analysis methods. The simulated fMRI dataset provided by various research institutions and researchers are mostly event/task-related. Resting-state fMRI analysis has been gaining importance recently for its ability to be used as a biomarker for various psychopathological conditions. Hence there is a need to generate simulated data for evaluation of the resting-state fMRI data analysis methods. In this paper, a method is proposed to simulate a complete 4D resting-state fMRI data using MATLAB. The fMRI data is simulated for normal and ADHD subject and the results are compared with real time data.","PeriodicalId":20006,"journal":{"name":"Periodico Di Mineralogia","volume":"42 1","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Periodico Di Mineralogia","FirstCategoryId":"89","ListUrlMain":"https://doi.org/10.37896/pd91.4/91475","RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GEOCHEMISTRY & GEOPHYSICS","Score":null,"Total":0}
引用次数: 0
Abstract
Novel methods for the analysis of functional magnetic resonance imaging (fMRI) data are being reported lately. It is necessary to validate these methods for reliability as the interpretations of the results are subjective as the ground truth in the fMRI data is not known. Validation of analysis methods requires knowledge of the ground truth of the data. Simulation studies are necessary to assess the quality of the statistical technique/analysis methods. The simulated fMRI dataset provided by various research institutions and researchers are mostly event/task-related. Resting-state fMRI analysis has been gaining importance recently for its ability to be used as a biomarker for various psychopathological conditions. Hence there is a need to generate simulated data for evaluation of the resting-state fMRI data analysis methods. In this paper, a method is proposed to simulate a complete 4D resting-state fMRI data using MATLAB. The fMRI data is simulated for normal and ADHD subject and the results are compared with real time data.
期刊介绍：
Periodico di Mineralogia is an international peer-reviewed Open Access journal publishing Research Articles, Letters and Reviews in Mineralogy, Crystallography, Geochemistry, Ore Deposits, Petrology, Volcanology and applied topics on Environment, Archaeometry and Cultural Heritage. The journal aims at encouraging scientists to publish their experimental and theoretical results in as much detail as possible. Accordingly, there is no restriction on article length. Additional data may be hosted on the web sites as Supplementary Information. The journal does not have article submission and processing charges. Colour is free of charges both on line and printed and no Open Access fees are requested. Short publication time is assured.
Periodico di Mineralogia is property of Sapienza Università di Roma and is published, both online and printed, three times a year.
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