Progestin-primed ovarian stimulation versus GnRH antagonist protocol in ICSI cycles in patients with different ovarian reserve: A retrospective cohort study

Abstract

Objective. To compare the ICSI cycle outcomes in PPOS Vs. conventional GnRh antagonist protocol. Patients and Methods. In this retrospective cohort study, 200 patients who were administrated gonadotropins for ovarian stimulation from the second or the third day of menstruation cycle were included in this study. When the follicular diameter reached 13-14 mm, GnRH antagonist was started in the group A, while in the group B,10 mg norethisterone acetate was taken daily orally. The retrieved oocytes were fertilized in vitro by intracytoplasmic sperm. Both groups underwent freeze-all and delayed embryo transfer. The primary outcome is the clinical pregnancy rate. The secondary outcomes included the duration, dosage & form of ovarian stimulation, the number & quality of oocytes retrieved which